Functionalized phthalocyanines: synthetic challenges for improved PDT outcomes
Phthalocyanines are good candidates as photosensitisers for photodynamic therapy because the macrocyclic core absorbs are far-red wavelengths. However, it is important to functionalise them to have a chance to better improve their suitability for PDT, for example by shifting up their absorption to near infrared wavelengths, or combining them to nanoparticles and attaching them to polymers.
However functionalization of phthalocyanines is often a synthetic challenge that will be presented.
“Phthalocyanines and porphyrazines” by Ümit İşci, Fabienne Dumoulin in Fundamentals of Porphyrin Chemistry: A 21st Century Approach - Eds M. O. Senge and P. Brothers. July 2022 - ISBN: 978-1-119-12928-8 doi.org/10.1002/9781119129301.ch5